Searchable abstracts of presentations at key conferences in endocrinology

ea0025p48 | Clinical biochemistry | SFEBES2011

Hypercortisolaemia in congenital adrenal hyperplasia: a diagnostic dilemma

Rajendran Rajesh , Morton John , Begley Joe , Fadl Abubakr , Richardson Tristan

Case report: A 67-year-old female with untreated congenital adrenal hyperplasia (21-hydoxylase deficiency) was diagnosed with bilateral vulval carcinomata. She was referred to another unit with serum sodium of 121 mmol/l, potassium 4.6 mmol/l and 17-hydroxyprogesterone of 714 nmol/l (0–14 nmol/l). A short synacthen test performed in the evening demonstrated a baseline cortisol of 558 nmol/l, rising to 643 nmol/l at 80 min. The baseline cortisol was deemed adequate but in ...